Springer Verlag New York Inc.
Tutti i libri editi da Springer Verlag New York Inc. - Pagina 6
Apoptosis in Carcinogenesis and Chemotherapy
George G. Chen , Paul B. S. Lai
editore: Springer Verlag New York Inc.
pagine: 406
Although research on carcinogenesis has focused more on cellular proliferation than on cell death, yet understanding the mechanism of apoptosis may have important implications for cancer therapy. This book brings together experts from around the world who will discuss the common cancers encountered in clinical practice in the laboratory setting. During the induction of these common cancers, the role of apoptosis in cellular and molecular changes is emphasized, critically highlighting possible anti-cancer strategies. For those who are interested in carcinogenesis and for those who are seeking new approaches to anti-cancer therapy, this book is an important reference. It serves not only as a reference of the current understanding of apoptosis in common cancers but also an important bridge between the laboratory and clinical practice. The editors and contributors are to be congratulated in bringing together an important pool of up-to-date knowledge to light and further our interest in this exciting and expanding ?eld. Arthur K. C.
Li Emeritus Professor of Surgery The Chinese University of Hong Kong v Preface The role of apoptosis in cancer development and emerging treatment strategies has rapidly expanded over the past few years. The novel discovery in the apoptotic pa- ways and their relevant molecules provides us not only the knowledge how tumors develop but also the opportunity to design new therapeutic tools to prevent or inhibit the growth of tumors with minimal side-effects. Undoubtedly, understanding the events involved at a molecular level can permit the manipulation of apoptosis for therapeutic purposes.
Knee Arthroscopy
Brian P. McKeon
,
James V. Bono
e altri
editore: Springer Verlag New York Inc.
pagine: 220
This book serves as a technique-oriented "how-to" guide to knee arthroscopy. Renowned authorities present advances in meniscal transplantation, articular cartilage repair, anterior cruciate ligament treatment and other procedures. Chapters are comprehensive, and readers are led step-by-step through techniques. Anatomy, indications, and complications for each approach are highlighted, and clinical pearls are featured throughout. Case studies facilitate the integration of concepts into practice. Orthopedic surgeons, orthopedic residents, and sports medicine physicians will find this thorough text invaluable.
Stem Cells and Cancer
Sadhan Majumder
editore: Springer Verlag New York Inc.
pagine: 312
Cancer is a primary cause of human mortality worldwide. Despite decades of basic and clinical research, the outcome for most cancer patients is still dismal. Some stumbling blocks to developing effective therapy include the heterogeneity of cancer tissues, the lack of knowledge about the critical molecular mechanisms in cancer tissues (which are typically aberrant compared with mechanisms in normal tissue), and the lack of good mechanism-based therapeutic approaches. The recent findings that most cancers contain a small fraction of self-renewing, differentiation-blocked stem cell-like cells (cancer stem cells) and that it is these cells-and not the major bulk of the tissue-that are the root cause for cancer initiation and metastasis have also highlighted the need to change our approach to cancer therapy. The objectives of this book, therefore, would be to impart up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies.
Molecular Pathology in Clinical Practice
Oncology
Debra G. B. Leonard
editore: Springer Verlag New York Inc.
pagine: 300
"Molecular Pathology in Clinical Practice: Oncology" is an authoritative and comprehensive guide that provides the general pathologist in clinical practice, as well as residents and fellows during their training, with the current standard in molecular oncology testing. It addresses all areas of molecular oncology testing including: molecular biology basics, inherited cancers, solid tumors, neoplastic hematopathology, identity testing and laboratory management. The book integrates the latest advancements in the field with the basic principles and practical applications.
Geriatric Oncology
Treatment, Assessment and Management
Arti Hurria , Lodovico Balducci
editore: Springer Verlag New York Inc.
pagine: 356
Cancer and aging are integrally related. Cancer incidence and mortality increase with age, with most cancer diagnoses and deaths occurring in patients aged 65 and older. The aging of the Baby Boomer population, along with an overall increase in life expectancy, points to a doubling of the U.S. population over age 65 by the year 2030. This demographic shift, combined with the known association of cancer and aging, is expected to bring about a rapid growth in the older cancer-patient population. It is clear that geriatric principles must become part of oncology care. The evaluation and development of treatment recommen- tions for an older adult with cancer can be challenging for many reasons. Tumor biology and response to therapy are affected by age. In addition, age-related factors may impact treatment patterns, tolerance, and efficacy. These age-related factors include functional status declines, comorbid conditions, changes in cognitive function, weakening of organ function, decreases in physiologic reserve, and faltering social support.
Surgical Anatomy and Technique
John Elias Skandalakis
,
Lee John Skandalakis
e altri
editore: Springer Verlag New York Inc.
pagine: 714
Surgical Anatomy and Technique: A Pocket Manual, consistently places in the top 10 bestsellers for Springer. The third edition will ensure its continued place on the list. The authors know exactly what makes this book popular: expansive scope; concise descriptions of anatomy and technique; illustrations on nearly every page; and its compact, portable size. The challenge, then, is in the very careful selection of topics and the need to be restrained in spite of the many surgical innovations that beg to be included but that have not yet stood the test of time. Toward that end, the third edition of Surgical Anatomy and Technique includes a limited amount of new material: 3 vascular procedures (abdominal aortic aneurysm, femoropopliteal bypass, and carotid endarterectomy) and 2 gynecologic procedures commonly performed by general surgeons (hysterectomy and oopherectomy). In addition, all of the existing chapters will be updated to reflect current surgical approaches and instrumentation. Third-year medical students, surgical residents and practicing surgeons will find this handbook to be one of their most-frequently-used resources.
The Achilles Tendon
James A. Nunley
editore: Springer Verlag New York Inc.
pagine: 272
Disorders of the Achilles tendon are universal, affecting people in a wide range of age groups. Because the Achilles tendon is one of the most pow- ful musculotendinous structures in the body, the impact of an injury to the Achilles tendon becomes magnified. There is a wide range of disorders or problems that can involve the insertional region, where pathology may rest with bone, tendon, or bursae. A completely different set of pathologic entities resides in the noninsertional region, one of which may include the frustrating degenerative tendinopathy. As our growing population ages but remains phy- cally active longer into life, the incidence of these disorders will continue to increase. I am proud to be given the opportunity to write the foreword to this text, which is intended for foot and ankle surgeons worldwide. Seldom does a book on a single entity become a current concepts review, as this work has. Too often, textbooks are not published for several years after the chapters have been written, making them obsolete upon publication. Not so with this book, which deals with timely topics on the Achilles tendon. Dr.
James Nunley has compiled this work in slightly over a year, thus providing the reader with sta- of-the-art material. Dr. Nunley had the foresight to create a much needed techniques-oriented book dealing with the complexities of the Achilles tendon. His approach was to develop a comprehensive guide to managing Achilles tendon problems.
Thin Calcium Phosphate Coatings for Medical Implants
Betty Leon , John Jansen
editore: Springer Verlag New York Inc.
pagine: 356
This book presents for the first time, the scattered novel results that have been achieved in very recent years in study on various thin calcium phosphate coatings produced by very diverse techniques. The comparison of thin calcium phosphate coatings with the thick plasma-sprayed ones is also included in the book. Readers will find a comprehensive book reviewing the state-of-the-art of the field with critical assessment of the achievements of the different preparation techniques.
Radiation Toxicity
A Practical Medical Guide
Gayle E. Woloschak , William Small
editore: Springer Verlag New York Inc.
pagine: 197
Radiation Toxicity: A Practical Guide provides insight into the management of day-to-day aspects of radiotherapy. Most radiation oncologists and radiation oncology nurses spend a large percentage of their time dealing with the effects of radiotherapy. This book describes the biology behind each sites acute and long-term responses to radiotherapy, including the best current knowledge regarding radiation tolerance, and fills a needed void in the literature that is available on radiation oncology.
Anesthesia Informatics
Jerry Stonemetz , Keith Ruskin
editore: Springer Verlag New York Inc.
pagine: 536
The ability to interface patient monitors directly to a computer, and generate a clinical record has existed for over 20 years. However, the acceptance of comprehensive electronic medical records in anesthesia has been slow to develop. Experts anticipate this reluctance is changing because of enhanced patient care through the use of detailed health information record systems. Anesthesia Informatics provides the health informatician and administrator with a comprehensive overview of this blossoming technology. With contributions from leaders in the field, this user-friendly guide addresses how this technology has enhanced both the need for and the ability to collect and apply data in an acute care setting. It also offers invaluable insight on the business implications and the rationales required to make a purchase decision. Each section outlines need to know information to help the reader with the implementation and utilization of an Anesthesia Information Management System. Useful case scenarios focus on the ideal components (anesthesia record, business rationale, communication, collaboration, and training) of a fully automated record-keeping system.
Musculoskeletal Ultrasound
Anatomy and Technique
John M. D O'Neill
editore: Springer Verlag New York Inc.
pagine: 348
Proper ultrasound examination and interpretation hinges on thorough knowledge of the relevant anatomy, artifacts, and technique. This book provides an excellent foundation by going beyond pathology and concentrating on these fundamentals. Basic physics and artifact recognition and prevention are outlined. Chapters review essential anatomy and include images and tables that highlight relevant bones, ligaments, tendons, muscles, and nerves. Sites of attachment and the best positions for examination are also noted. Technique is presented via a three-tiered approach and photographs of patients in the transducer position are matched with the resulting ultrasound images and complementary anatomical overlays.
Handbook of Childhood and Adolescent Obesity
Elissa Jelalian , Ric G. Steele
editore: Springer Verlag New York Inc.
pagine: 516
Now, in one comprehensive, easy-to-access volume, this essential handbook lays bare the scope of the growing problem of childhood and adolescent obesity. It goes further, too, examining the impact of the epidemic in terms of its psychological burden, its health consequences, and the available prevention and treatment options. Editors Jelalian and Steele have ensured that the chapters utilize the most up-to-date empirical and clinical knowledge available. This volume provides readers not only raw data, but also a framework for translating findings into effective, efficient practice -- assessment, treatment, and prevention. It will be required reading for a host of professionals, from psychologists to social workers and medical practitioners.
Methods of Cancer Diagnosis, Therapy and Prognosis
Breast Carcinoma
M. A. Hayat
editore: Springer Verlag New York Inc.
pagine: 776
The enormity of the global healthcare costs vical. One-fifth of all cancers worldwide as a result of cancer infliction cannot be are caused by a chronic infection, for overemphasized. There are more than 100 example, human papilloma virus (HPV) types of cancers; any part of the body can causes cervical cancer and hepatitis B be affected. More than 11 million people virus (HBV) causes liver cancer. Tobacco are diagnosed with cancer every year, and use is the most common preventable cause it is estimated that there will be 16 mil- of cancer in the world. Approximately, lion new cases per year by the year 2020. 168,000 cancer deaths are expected to be In 2005, 7. 6 million people died of can- caused by tobacco use. Approximately, cer, that is, 13% of the 58 million deaths 40% of cancer could be prevented, mainly worldwide. It is estimated that 9 million by not using tobacco, having a healthy people will die from cancer worldwide in diet, being physically active, preventing 2015 and 11. 4 million will die in 2030. infections that may cause cancer, reduc- More than 70% of all cancer deaths occur ing exposure to sunlight, and avoidance of in low and middle income countries. excessive alcohol consumption and stress Five major cancer causing overall mor- (anger).
A third of cancers could be cured talities per year worldwide are (WHO): if detected early and treated adequately. It is well established that scientific 1. Lung: 1.
Handbook of Ambulatory Anesthesia
Beverly K. Philip , Rebecca S. Twersky
editore: Springer Verlag New York Inc.
pagine: 500
This second edition of the Handbook of Ambulatory Anesthesia has been completely updated and expanded to reflect current practice guidelines and trends in ambulatory anesthesia. This practical manual covers preoperative evaluation, patient and procedure selection, anesthetic techniques, postoperative management, and quality assurance. Additionally, the editors have included all new information on anesthesia for minimally invasive surgery as well as office-based procedures. Written and edited by experts who have developed successful practices at the world's leading institutions, Handbook of Ambulatory Anesthesia includes a broad representation of perspectives and approaches for practitioners in every ambulatory setting.
Skeletal Muscle Repair and Regeneration
Stefano Schiaffino , Terence Partridge
editore: Springer Verlag New York Inc.
pagine: 392
Since the middle of the last century we have progressively built up a comprehensive descriptive model of the allied mechanisms that maintain our muscles at a size and strength appropriate to the functional demands upon them and that rapidly repair damaged muscles. This volume is an assemblage of the collective experience from the pick of major research groups investigating these aspects of muscle cell biology. It provides up-to-date coverage and presents a broad range of topics.
Primer on the Rheumatic Diseases
John H. Klippel
,
John H. Stone
e altri
editore: Springer Verlag New York Inc.
pagine: 740
This is one of the most prestigious and comprehensive texts on arthritis and related diseases, including osteoarthritis, rheumatoid arthritis, osteoporosis, lupus and more than one hundred others. It offers medical students and physicians a concise description of the current science, diagnosis, clinical consequences, and principles of management. New and expanded chapters heighten the translational nature of this edition. Students, trainees, and practicing clinicians all need a standard textbook that can change with the times and reflect recent strides taken in understanding and treating rheumatic disease. The Primer fills that need.
Breast MRI
Fundamentals and Technical Aspects
R. Edward Hendrick
editore: Springer Verlag New York Inc.
pagine: 270
With a focus on the basic imaging principles of breast MRI rather than on mathematical equations, this book takes a practical approach to imaging protocols, which helps radiologists increase their diagnostic effectiveness. It walks the reader through the basics of MRI, making it especially accessible to beginners. From a detailed outline of equipment prerequisites for obtaining high quality breast MRI to instructions on how to optimize image quality, expanded discussions on how to obtain optimized dynamic information, and explanations of good and bad imaging techniques, the book covers the topics that are most relevant to performing breast MRI.
Arthroscopic Rotator Cuff Surgery
A Practical Approach to Management
Jeffrey S. Abrams , Robert H. Bell
editore: Springer Verlag New York Inc.
pagine: 393
This text takes a comprehensive approach to rotator cuff disorders, including tears and arthroscopic techniques in surgical management. It addresses the latest topics, such as the conversion of mini-open repair to all arthroscopic repair, and answers key questions raised at instructional courses. Experts in the field present not only arthroscopic shoulder anatomy, cuff tear patterns, repair concepts, and other fundamentals, but also provide coverage of state-of-the-art techniques. The step-by-step approach is supplemented by a wealth of anatomical drawings and color photos.
Atlas of Ultrasound and Nerve Stimulation Guided Regional Anesthesia
Ban Tsui
editore: Springer Verlag New York Inc.
pagine: 325
The Atlas of Ultrasound and Nerve Stimulation-Guided Regional Anesthesia shows how to use ultrasound technology and how to master guided nerve stimulation techniques to achieve consistently good results. Throughout the book, ultrasound images are correlated with MRIs to enhance anatomic identification. In addition, peripheral nerve block techniques for upper and lower extremities and the trunk are demonstrated step by step. With visualized needle placement and the ability to see the nerves, ultrasound and nerve stimulation-guided techniques instill confidence in the anesthesiologist, offer safety to patients, and enhance the efficient use of time in the operating room.
Biomaterials
An Introduction
Joon Bu Park , Roderic S. Lakes
editore: Springer Verlag New York Inc.
pagine: 574
With sixty years of combined experience, the authors of this extensively revised book have learned to emphasize the fundamental materials science, structure-property relationships, and biological responses as a foundation for a wide array of biomaterials applications. This edition includes a new chapter on tissue engineering and regenerative medicine, approximately 1900 references to additional reading, extensive tutorial materials on new developments in spinal implants and fixation techniques and theory. It also offers systematic coverage of orthopedic implants, and expanded treatment of ceramic materials and implants.
