Elsevier - Health Sciences Division

Offering focused, practical, and up-to-date content on immunotherapies used to treat a wide variety of cancer types, Clinical Immuno-Oncology covers the basic cellular and molecular mechanisms involved in cancer initiation and progression. The text reviews the development of tumor specific antigens and the challenges of developing cancer immunotherapies. Every effort is made to relate the fundamental aspects of host immunity to the efficacy of current immunotherapies and how they work in conjunction with the immune system to combat cancer. This foundational resource explains the basics of cancer immunotherapy, discusses best practices, and provides recommendations from experienced clinicians in the field. Dr. John E. Niederhuber and a team of expert contributing authors provide clinically focused information essential for integrating these new therapies into practice-making this an ideal resource for fellows, practitioners, and other cancer team members in medical oncology, radiation oncology, cancer surgery, immunology, and cancer research. Offers balanced and synthesized content on clinical science, clinical and translational research, and evidence-based practice for cutting-edge immunotherapies Discusses clinical applications of immunotherapies in common types of cancer including melanoma, breast cancer, pancreatic cancer, colon and rectum cancer, prostate cancer, leukemias, and hematologic malignancies Includes dedicated chapters on immune responses, innate immunity, active immunization against cancer, and cell-based therapies by leading experts Covers key topics such as cancer immunotherapy in the presence of COVID-19, immunotherapeutics, new findings concerning the role of the microbiome in immunotherapy, advances in engineered cell-based therapies, and active immunization against cancer An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Easy to read and follow, Essentials of Equipment in Anaesthesia, Critical Care and Perioperative Medicine makes an otherwise dry subject digestible and easy to learn. This practical textbook comprehensively covers all the equipment used in the operating theatre and intensive care unit, including why it is used and any related safety concerns. It has been fully updated in its sixth edition to include new technologies introduced during the Covid-19 pandemic. This is ideal as the main text for all trainees undertaking the primary FRCA exams and is also suitable anyone who works with anaesthetic equipment, including anaesthetic and intensive care nurses and operating department practitioners. It features concise and consistent text and illustrations, self-assessment features, and exam tips. Portable, concise and simply formatted - a perfect practical companion Clear coloured images and illustrations bring the text to life Follows the Royal College of Anaesthetists postgraduate training and exam syllabus Summary boxes, more than 100 exam style questions, and OSCE stations and exam tips all aid the reader in exam revision

**Selected for 2026 Doody's Core Titles as an Essential Purchase in Physiology** Pairing necessary detail with concise readability, Berne & Levy Physiology, 8th Edition, provides a perfect balance of content to deliver an in-depth understanding of the body’s dynamic processes. Long respected for its scientifically rigorous approach, this highly regarded, mid-size text offers essential physiology with integrated coverage of biophysics andkey experimental observations and examples-all designed to provide a solid scientific foundation in physiology for future scientists and clinicians. Uses a logical, organ system-based approach that clearly describes all of the mechanisms that control and regulate bodily function Includes new clinical case examples, as well as In the Clinic and At the Molecular Level boxes that highlight practical aspects of this fundamental science Provides key experimental observations and examples that offer a rich understanding of the body's dynamic processes Discusses recent discoveries such as the role of lymphatics in the nervous system Begins each chapter with a bulleted list of questions and ends with key concepts covered in that chapter Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices

**Selected for 2026 Doody's Core Titles in Pharmacology** Rang and Dale’s Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing. Comprehensive information on drug mechanisms, basic physiology and biochemistry, and underlying pathophysiology of disease - suitable for students from many disciplines Clear figures to aid understanding, including data figures as well as mechanistic diagrams, Key points box summaries, clinical boxes and colour-coded chapters help to master difficult concepts Emphasis on therapeutic drugs to help apply theory to practice Over 150 questions and 12 clinical cases to test your knowledge An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customise your content, make notes and highlights, and have content read aloud

**Selected for 2026 Doody's Core Titles in Emergency Medicine** While medical specialists in disaster mitigation, preparedness, and response are needed worldwide, the initial phase of disaster response is almost entirely dependent upon local resources-making it essential that all healthcare personnel have a working knowledge of the field and stand ready to integrate into the response system. Ciottone's Disaster Medicine, 3rd Edition, is the most comprehensive reference available to help accomplish these goals in every community. It thoroughly covers isolated domestic events as well as global disasters and humanitarian crises. Dr. Gregory Ciottone and more than 200 worldwide authorities share their knowledge and expertise on the preparation, assessment, and management of both natural and man-made disasters, including lessons learned by the responders to contemporary disasters such as the COVID-19 pandemic, Australian and western U.S. wildfires, European heatwaves, the Beirut explosion, recent hurricanes and typhoons, and the global refugee crisis. Part 1 offers an A-to-Z resource for every aspect of disaster medicine and management, while Part 2 features an exhaustive compilation of every conceivable disaster event, organized to facilitate quick reference in a real-time setting Covers basic concepts such as identification of risks, organizational preparedness, equipment planning, disaster education and training, and more advanced concepts such as disaster risk reduction, health in complex emergencies, building local disaster resiliency, psychological impact of disasters on children, and more Contains new decision trees throughout that help guide you through the decision-making process in difficult situations Uses an easy-to-follow, templated approach to historical perspectives, overviews of current practice including pre-incident and post-incident actions, medical treatment of casualties, and potential pitfalls Includes updated sections on man-made disasters, including mass casualties, active shooter situations, integrated response to terrorist attacks, and chemical/biological/radiological/nuclear/high-yield explosives disasters Discusses the latest technologies, such as the use of mobile disaster applications, drone response systems, and virtual reality simulation training Features thoroughly updated information on crisis leadership, practical applications of disaster epidemiology, disaster and climate change, and the integration of non-government agencies (NGOs) in disaster response-a critical topic for those responding to humanitarian needs overseas Includes new chapters on Pandemic Preparedness and Response, Disaster Medicine in a Changing Climate, Disaster Response in Asia, Building Local Capacity and Disaster Resiliency, Civilian-Military Coordination in Disaster Response, Medical Simulation in Disaster Preparedness, Disaster Nursing, Crisis Meta-Leadership, Palliative Care in Disasters, Counter-Terrorism Medicine, SARS CoV (COVID-19 and SARS), and Disasters in Space Travel An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Ideal for exam preparation and everyday clinical practice, Fetal, Neonatal and Pediatric Neuroradiology brings you fully up to date with recent advances in knowledge and image quality in this fast-changing field. World-renowned pediatric neuroradiologist Dr. Thierry A. G. M. Huisman, along with expert coauthors Drs. Stephen Kralik, Nilesh Desai, and Avner Meoded, utilizes an easy-to-read, quick-reference format of bulleted lists and high-quality images to enhance your understanding and help you quickly grasp and retain critical information. Balances state-of-the-art images and clinical features pertinent to the diagnosis in a bulleted format for quick reference and identification Includes more than 400 diagnoses encountered in pediatric, neonatal, and fetal neuroimaging, including brain, head, neck, spine, and metabolic disorders Features thousands of high-quality MRI, CT, ultrasound, and radiographic images An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Completely revised and updated, Avery's Diseases of the Newborn, 11th Edition, remains your #1 choice for clinically focused, cutting-edge guidance on the evaluation, diagnosis, and treatment of diseases of the newborn. Drs. Christine A. Gleason, Taylor Sawyer, and a team of expert contributing authors provide comprehensive, up-to-date coverage of every key disease and condition affecting newborns, keeping you current in this fast-changing field. You’ll find the specific strategies you need to confidently provide care for this unique patient population, in a full-color, easy-to-use single volume that focuses on key areas of practice. Reflects the latest developments on all aspects of newborn evaluation and management, featuring new content, new chapters, new contributors, and fresh perspectives from a new co-editor Brings you the latest on current topics such as perinatal/neonatal COVID-19, genomics and precision medicine, acute and chronic neonatal respiratory disorders, brain injury and neuroprotection, necrotizing enterocolitis, probiotics, palliative care, prenatal drug exposure, retinopathy of prematurity, and more Provides clinically relevant, practical guidance in concise, focused chapters that include summary boxes, suggested readings, and more than 500 full-color illustrations, micrographs, and photographs Contains the 2020 American Academy of Pediatrics and American Heart Association neonatal resuscitation guidelines and the 2022 American Academy of Pediatrics guidelines on the management of hyperbilirubinemia Serves as a reliable quick reference for clinical questions and an excellent resource for board review An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Spinal Fusion Techniques, a volume in the Atlas of Interventional Pain Management series, is a concise, practical guide that provides clinicians with detailed, step-by-step guidance on how to perform the latest interventional techniques for treating patients with chronic pain as a result of spinal stenosis. This comprehensive, easy-to-follow guide offers expert coverage of how to deliver safe, accurate, and cost-effective pain relief to patients using all clinically useful imaging modalities, including ultrasound-guided techniques and fluoroscopy. With high-quality images and clear, authoritative guidance throughout, it shows exactly how to evaluate the causes of pain, identify the most promising stimulation technique, locate the site with precision, and deliver effective relief. Offers a comprehensive overview of the latest techniques used in spinal fusion Features clinically relevant anatomic drawings and radiologic images that provide step-by-step instruction on techniques Provides clear guidance on the risks and benefits, as well as indications and contraindications, for each procedure Covers key topics such as Minimally Invasive Posterior Lumbar Fusion: A Novel Approach to Facet Fusion; Posterior Spinal Fusion; and Interspinous Fusion with Lateral Percutaneous Technique Includes easy-to-follow, templated content on patient selection, preoperative prep, and post-operative care Contains full-color line drawings, photographs, and ultrasound images that provide you with a firm grasp of the anatomy and equipment involved with each procedure Highlights potential pitfalls for each technique and offers clinical pearls on how to avoid them An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

**Selected for 2026 Doody's Core Titles as an Essential Purchase in Nephrology** Written for fellows, practicing nephrologists, and internists who treat patients with disorders affecting the renal system, Comprehensive Clinical Nephrology, 7th Edition, offers a practical approach to this complex field, supported by underlying scientific facts and pathophysiology. World leaders in nephrology provide current information on clinical procedures and conditions, covering everything from fluid and electrolyte disorders to hypertension, diabetes, dialysis, transplantation, and more-all in a single, convenient volume. Provides a "just right" amount of basic science and practical clinical guidance to help you make efficient and informed decisions Contains new chapters on Blood Pressure Management in the Dialysis Patient, Kidney Diseases Associated with Corona Viruses, Ultrasound Imaging in Nephrology, and Radiologic and Nuclear Imaging in Nephrology Includes more than 1,500 full-color illustrations that highlight key topics and detail pathogenesis for a full range of kidney conditions and clinical management Covers key topics such as COVID-19, chronic kidney disease, end stage kidney disease, kidney transplantation, glomerular disease, onco-nephrology, dialysis, and much more Features popular, color-coded algorithms that provide easy access to important content: yellow boxes for general information, green boxes for therapeutic intervention, and blue boxes for necessary investigations Includes quick-reference boxes with links to clinical guidelines in all relevant chapters, plus self-assessment questions online An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

**Selected for Doody’s Core Titles® 2024 with "Essential Purchase" designation in Infectious Disease** From the latest vaccination evidence, recommendations, and protocols . . . to new vaccine development and the use of vaccines in reducing disease, Plotkin’s Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin’s Vaccines is a must-have reference for current, authoritative information in this fast-moving field. Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues Analyzes the cost-benefit and cost-effectiveness of different vaccine options Helps you clearly visualize concepts and objective data through an abundance of tables and figures Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices

Fifty years since it was first published and now fully revised, Macleod’s remains the textbook of choice for medical students, junior doctors, nurses and allied health practitioners who understand that excellence in clinical examination is integral to good practice. The fifteenth edition will teach you how to take a history and carry out proficient clinical examination, in order to elicit the key clinical symptoms and signs of disease. It covers general principles, relevant history, examination and investigations for all the major body systems - and how to effectively apply these skills to specific clinical situations and prepare for assessment. Macleod’s Clinical Examination is enhanced with 32 supplementary videos demonstrating key clinical examination routines described in the book, many new and revised for this edition in line with latest guidance and best practice. Primarily focused on the practical skills required by medical students and early career stage clinicians Explains the physical basis of clinical signs to aid understanding Introduces the formulation of a differential diagnosis Provides logical initial investigations for each body system Comes with access to the complete, fully searchable and downloadable eBook

Concise, readable text and an outstanding art program make Gray's Anatomy for Students, 5th Edition, your go-to text for essential information in human anatomy. This fully revised volume focuses on the core information medical students need to know, in an easy-access format and with additional multimedia content to facilitate effective study and mastery of the material. A team of expert authors share a wealth of diverse teaching and clinical experience—all enhanced by more than 1,000 innovative, original illustrations by renowned illustrators Richard Tibbitts and Paul Richardson, who capture anatomical features with unrivalled clarity.

**Selected for 2026 Doody's Core Titles in Transplantation Surgery** Led by authors from MD Anderson’s Stem Cell Transplantation and Cellular Therapy Department, the world’s largest and highly respected program at the forefront of rapidly advancing treatments in the field, Manual of Hematopoietic Cell Transplantation and Cellular Therapies is a comprehensive, focused reference covering the latest clinical developments and applications of stem cell transplant and cellular therapies for hematologic malignancies and solid tumors. This cutting-edge title, with a majority contribution from the MD Anderson Cancer Center and leading faculty from other academic institutions, covers breakthrough cell-based therapies for various diseases including lymphoma, multiple myeloma, leukemia, and select solid tumor and autoimmune diseases. This unique, definitive resource is essential for hematologists, fellows in hematology and immunotherapy, mid-level providers, pharmacists, and oncologists who refer patients for cell-based therapies. Addresses hematologic conditions including leukemia, lymphoma, and myeloma Offers guidance on hematopoietic cell transplantation for solid tumors Covers basic science principles, clinical aspects, pharmacology, radiation therapy, and disease-specific guidelines, including prevention and management of complications Discusses key topics such as hematopoietic cell collection, bone marrow harvesting, umbilical cord blood transplantation, CAR T-cell therapy, and patient/donor selection and preparation of HCT Features extensive summary boxes, bulleted content, and algorithms throughout for quick and easy reference Offers team-based, clinically-focused coverage from world-renowned leaders in the field An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

**Selected for 2026 Doody's Core Titles in Critical Care** Bridging the gap between medical and surgical specialties in critical care, Textbook of Critical Care, 8th Edition, offers a practical, multidisciplinary approach to the effective management of adult and pediatric patients in the ICU. An outstanding editorial team, led by world-renowned intensivist Dr. Jean-Louis Vincent, assisted by Dr. Frederick A. Moore and new editors Drs. Rinaldo Bellomo and John J. Marini, provides the evidence-based guidance you need to overcome a full range of practice challenges. A full-color art program, relevant basic science and key summary points in every chapter, and expert contributing authors from all over the world make this an indispensable resource for every member of the critical care team. Provides a concise, readable understanding of the pathophysiology of critical illness and new therapeutic approaches to critical care Addresses both medical and surgical aspects in critical care for adult and pediatric patients in one comprehensive, easy-to-use reference Shares the knowledge and expertise of the most recognized and trusted leaders in the field, with more international contributing authors than in previous editions Covers new information on procedural and diagnostic ultrasound, prone positioning, ECMO, and VADs Discusses key topics such as organ support, telemedicine, echocardiography, antibiotic stewardship, antiviral agents, coagulation and anti-coagulation, and more Features a wealth of tables, boxes, algorithms, diagnostic images, and key points that clarify important concepts and streamline complex information for quick reference Includes companion videos and exclusive chapters online that cover commonly performed procedures Takes a multidisciplinary approach to critical care, with contributions from experts in anesthesia, surgery, pulmonary medicine, and pediatrics Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices

Offering rapid, portable access to key concepts and principles of pathology from Robbins and Cotran Pathologic Basis of Disease, 10th Edition, this up-to-date Pocket Companion makes it easy to locate essential information on the go. The condensed, at-a-glance format, organized to parallel the parent text, is ideal for quick review-anytime, anywhere. Features cutting-edge information on important topics such as novel therapies for hepatitis C, personalized medicine, the role of microbiome and metabolome in non-communicable disease, and much more Includes new gross and microscopic figures for clarity of morphology and new artwork depicting the latest advances in molecular pathogenesis of cancers Reflects updated page references and content changes found in to Robbins and Cotran Pathologic Basis of Disease, 10th Edition Contains all the key data and principles needed for the USMLE Step 1, in-course exams, and rotations Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices

For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Pediatric Hematology & Oncology Secrets, 2nd Edition, offers practical, up-to-date coverage of the full range of essential topics in this dynamic field. This highly regarded resource features the Secrets’ popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style - making inquiry, reference, and review quick, easy, and enjoyable. The proven Secrets Series® format gives you the most return for your time - succinct, easy to read, engaging, and highly effective Fully revised and updated, including discussions of supportive care of children with cancer and psychosocial aspects of care New chapters on Precision Medicine and Systems Biology; Health Equity and Disparities in Pediatric and Adolescent/Young Adult Oncology; Transfusion Medicine; Neoplastic Hematopathology; Hemophagocytic Lymphohistiocytosis; and more Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams Bulleted lists, mnemonics, practical tips from global leaders in the field - all providing a concise overview of important board-relevant content Portable size makes it easy to carry with you for quick reference or review anywhere, anytime Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices